Ethyl 2-amino-4,5-dihydro-3-furoate → HCID 20130711, compound

HRID 845992Notes

Reaction equation

HRID 845992 reaction equation
[Cl:1][C:2]1[CH:13]=[C:12]([F:14])[C:11]([N:15]=[C:16]=[O:17])=[CH:10][C:3]=1[C:4]([O:6][CH:7]([CH3:9])[CH3:8])=[O:5].[NH2:18][C:19]1[O:20][CH2:21][CH2:22][C:23]=1[C:24]([O:26][CH2:27][CH3:28])=[O:25]>>[Cl:1][C:2]1[CH:13]=[C:12]([F:14])[C:11]([NH:15][C:16]([NH:18][C:19]2[O:20][CH2:21][CH2:22][C:23]=2[C:24]([O:26][CH2:27][CH3:28])=[O:25])=[O:17])=[CH:10][C:3]=1[C:4]([O:6][CH:7]([CH3:8])[CH3:9])=[O:5]

Participants

3

Reactant 2

HCID 120136Ethyl 2-amino-4,5-dihydro-3-furoateHCID 13519895Isopropyl 2-chloro-4-fluoro-5-isocyanatobenzoate

Product 1

HCID 20130711HCID 20130711, compound

Procedure

using isopropyl 2-chloro-4-fluoro-5-isocyanatobenzoate and ethyl 2-amino-4,5-dihydrofuran-3-carboxylate there is obtained isopropyl 2-chloro-4-fluoro-5-{3-[3-(ethoxycarbonyl)-4,5-dihydro-furan-2-yl]ureido}-benzoate.

Sources & evidence

ORD record
ord-9157a68b4ffc4619ae433fe9d6359b55
Source dataset
uspto-grants-1988_07
Patent number
US04760163

Reaction notes

Loading…