(1-Aminoethylidene)propanedinitrile → HCID 20130596, compound

HRID 845996Notes

Reaction equation

HRID 845996 reaction equation
[NH2:1][C:2]([CH3:8])=[C:3]([C:6]#[N:7])[C:4]#[N:5].[Cl:9][C:10]1[CH:21]=[C:20]([F:22])[C:19]([N:23]=[C:24]=[O:25])=[CH:18][C:11]=1[C:12]([O:14][CH:15]([CH3:17])[CH3:16])=[O:13]>>[NH2:5][C:4]1[N:23]([C:19]2[C:20]([F:22])=[CH:21][C:10]([Cl:9])=[C:11]([CH:18]=2)[C:12]([O:14][CH:15]([CH3:17])[CH3:16])=[O:13])[C:24](=[O:25])[N:1]=[C:2]([CH3:8])[C:3]=1[C:6]#[N:7]

Participants

3

Reactant 2

HCID 12525758(1-Aminoethylidene)propanedinitrileHCID 13519895Isopropyl 2-chloro-4-fluoro-5-isocyanatobenzoate

Product 1

HCID 20130596HCID 20130596, compound

Procedure

using 3-amino-2-cyanocrotononitrile and isopropyl 2-chloro-4-fluoro-5-isocyanatobenzoate there is obtained isopropyl 5-[6-amino-5-cyano-4-methyl-2-oxo-1(2H)-pyrimidinyl]-2-chloro-4-fluorobenzoate, m.p. 255°-257° C.

Sources & evidence

ORD record
ord-4b6de11168f74763af3eb4d93ae6946f
Source dataset
uspto-grants-1988_07
Patent number
US04760163

Reaction notes

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