Putrescine → HCID 14884399, compound

HRID 846097Notes

Reaction equation

HRID 846097 reaction equation
[CH3:1][CH:2]1[C:7]([C:8]2[CH:9]=[CH:10][C:11]3[O:15][C:14](SC)=[N:13][C:12]=3[CH:18]=2)=[N:6][NH:5][C:4](=[O:19])[CH2:3]1.[NH2:20][CH2:21][CH2:22][CH2:23][CH2:24][NH2:25]>O>[CH3:1][CH:2]1[C:7]([C:8]2[CH:9]=[CH:10][C:11]3[O:15][C:14]([NH:20][CH2:21][CH2:22][CH2:23][CH2:24][NH2:25])=[N:13][C:12]=3[CH:18]=2)=[N:6][NH:5][C:4](=[O:19])[CH2:3]1

Participants

4

Reactant 2

HCID 1045PutrescineHCID 151078155-methyl-6-(2-methylthiobenzoxazol-5-yl)-4,5-dihydro-3(2H)-pyridazinone

Product 1

HCID 14884399HCID 14884399, compound

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Procedure

4.1 g (15.0 mmol) of 5-methyl-6-(2-methylthiobenzoxazol-5-yl)-4,5-dihydro-3(2H)-pyridazinone and 15 ml of 1,4-diaminobutane are heated to 60° C. for 45 minutes, then stirred into 200 ml of water and left to crystallise at ambient temperature. After about 30 minutes the product is suction filtered, washed with about 50 ml of water and dried at 60° C. in a circulating air dryer.

Workup

  1. waitleft
  2. customto crystallise at ambient temperature
  3. filtrationsuction filtered
  4. washwashed with about 50 ml of water
  5. customdried at 60° C. in a circulating air dryer

Sources & evidence

ORD record
ord-c09157431c734fb081eb5a89edd16a6d
Source dataset
uspto-grants-1992_08
Patent number
US05135932

Reaction notes

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