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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 846112Generated: October 30, 2026

1-[4-(2-Isobutoxyethyl)phenoxy]-2,3-epoxypropane → 6-[4-[2-[3-(4-(2-Isobutoxy-ethyl)phenoxy)-2-hydroxypropylamino]ethoxy]-3-chloro-phenyl]-4,5-dihydro-3(2H)-pyridazinone

https://huagongshe.com/reaction/846112

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-[4-(2-Isobutoxyethyl)phenoxy]-2,3-epoxypropaneHCID 15107806—
Reactant6-[4-(2-aminoethoxy)-3-chloro-phenyl]-4,5-dihydro-3(2H)-pyridazinoneHCID 15107822—
Product6-[4-[2-[3-(4-(2-Isobutoxy-ethyl)phenoxy)-2-hydroxypropylamino]ethoxy]-3-chloro-phenyl]-4,5-dihydro-3(2H)-pyridazinoneHCID 14884424—

Reaction Steps

Prepared analogously to Example 1 from 1-[4-(2-isobutoxy-ethyl)-phenoxy]-2,3-epoxypropane and 6-[4-(2-aminoethoxy)-3-chloro-phenyl]-4,5-dihydro-3(2H)-pyridazinone.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05135932
Source datasetuspto-grants-1992_08
ORD IDord-a1d4a56e184347c5a49ffd282ce1464e
Source noteuspto-grants-1992_08