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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 846114Generated: October 31, 2026

2-[(2-Chloro-5-methylphenoxy)methyl]oxirane → 6-[4-[2-[3-(2-Chloro-5-methyl-phenoxy)-2-hydroxypropylamino]ethoxy]phenyl]-4,5-dihydro-5-methyl-3(2H)-pyridazinone

https://huagongshe.com/reaction/846114

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-[(2-Chloro-5-methylphenoxy)methyl]oxiraneHCID 13012836—
Reactant6-[4-(2-aminoethoxy)phenyl]-4,5-dihydro-5-methyl-3(2H)-pyridazinoneHCID 15107823—
Product6-[4-[2-[3-(2-Chloro-5-methyl-phenoxy)-2-hydroxypropylamino]ethoxy]phenyl]-4,5-dihydro-5-methyl-3(2H)-pyridazinoneHCID 15107825—

Reaction Steps

Prepared analogously to Example 1 from 1-(2-chloro-5-methylphenoxy)-2,3-epoxypropane and 6-[4-(2-aminoethoxy)phenyl]-4,5-dihydro-5-methyl-3(2H)-pyridazinone.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05135932
Source datasetuspto-grants-1992_08
ORD IDord-e037c817ab87442ebfa4bf45c6ac78f3
Source noteuspto-grants-1992_08