6-[4-(2-aminoethoxy)phenyl]-4,5-dihydro-5-methyl-3(2H)-pyridazinone → HCID 178429572, compound

HRID 846117Notes

Reaction equation

HRID 846117 reaction equation
[OH:1][C:2]1[CH2:11][CH2:10][C:9]2[C:4](=[CH:5][CH:6]=[CH:7][C:8]=2[O:12][CH2:13][CH:14]2[O:16][CH2:15]2)[N:3]=1.[NH2:17][CH2:18][CH2:19][O:20][C:21]1[CH:26]=[CH:25][C:24]([C:27]2[CH:28]([CH3:34])[CH2:29][C:30](=[O:33])[NH:31][N:32]=2)=[CH:23][CH:22]=1>>[OH:1][C:2]1[CH2:11][CH2:10][C:9]2[C:4](=[CH:5][CH:6]=[CH:7][C:8]=2[O:12][CH2:13][CH:14]([OH:16])[CH2:15][NH:17][CH2:18][CH2:19][O:20][C:21]2[CH:22]=[CH:23][C:24]([C:27]3[CH:28]([CH3:34])[CH2:29][C:30](=[O:33])[NH:31][N:32]=3)=[CH:25][CH:26]=2)[N:3]=1

Participants

3

Reactant 2

HCID 151078236-[4-(2-aminoethoxy)phenyl]-4,5-dihydro-5-methyl-3(2H)-pyridazinoneHCID 178517176HCID 178517176, compound

Product 1

HCID 178429572HCID 178429572, compound

Procedure

Prepared analogously to Example 1 from 1-(3,4-dihydro-2-hydroxy-quinolin-5-yloxy)-2,3-epoxypropane and 6-[4-(2-aminoethoxy)phenyl]-4,5-dihydro-5-methyl-3(2H)-pyridazinone.

Sources & evidence

ORD record
ord-782d1ad1f5a4499f803d3e64d5831710
Source dataset
uspto-grants-1992_08
Patent number
US05135932

Reaction notes

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