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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 846119Generated: October 27, 2026

6-[4-(2-aminoethoxy)-phenyl]-4,5-dihydro-3(2H)-pyridazinone → 6-[4-[2-[3-(4-((2-Isopropoxyethoxy)methyl)phenoxy)-2-hydroxypropylamino]ethoxy]phenyl]-4,5-dihydro-3(2H)-pyridazinone

https://huagongshe.com/reaction/846119

Reaction equation

Participants

RoleNameHCIDCharge
Reactant6-[4-(2-aminoethoxy)-phenyl]-4,5-dihydro-3(2H)-pyridazinoneHCID 14441866—
Reactant2-((4-((2-(1-Methylethoxy)ethoxy)methyl)phenoxy)methyl)oxiraneHCID 15107809—
Product6-[4-[2-[3-(4-((2-Isopropoxyethoxy)methyl)phenoxy)-2-hydroxypropylamino]ethoxy]phenyl]-4,5-dihydro-3(2H)-pyridazinoneHCID 14884427—

Reaction Steps

Prepared analogously to Example 1 from 1-[4-((2-isopropoxyethoxy)methyl)phenoxy]-2,3-epoxypropane and 6-[4-(2-aminoethoxy)-phenyl]-4,5-dihydro-3(2H)-pyridazinone.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05135932
Source datasetuspto-grants-1992_08
ORD IDord-92832274eb7b453d88bee0aefda6e37f
Source noteuspto-grants-1992_08