6-[2-(2-aminoethyl)benzimidazol-5-yl]-4,5-dihydro-5-methyl-3(2H)-pyridazinone → HCID 178429555, compound

HRID 846135Notes

Reaction equation

HRID 846135 reaction equation
[OH:1][C:2]1[CH2:11][CH2:10][C:9]2[C:4](=[CH:5][CH:6]=[CH:7][C:8]=2[O:12][CH2:13][CH:14]2[O:16][CH2:15]2)[N:3]=1.[NH2:17][CH2:18][CH2:19][C:20]1[NH:21][C:22]2[CH:28]=[C:27]([C:29]3[CH:30]([CH3:36])[CH2:31][C:32](=[O:35])[NH:33][N:34]=3)[CH:26]=[CH:25][C:23]=2[N:24]=1>>[OH:1][C:2]1[CH2:11][CH2:10][C:9]2[C:4](=[CH:5][CH:6]=[CH:7][C:8]=2[O:12][CH2:13][CH:14]([OH:16])[CH2:15][NH:17][CH2:18][CH2:19][C:20]2[NH:21][C:22]3[CH:28]=[C:27]([C:29]4[CH:30]([CH3:36])[CH2:31][C:32](=[O:35])[NH:33][N:34]=4)[CH:26]=[CH:25][C:23]=3[N:24]=2)[N:3]=1

Participants

3

Reactant 2

HCID 144040656-[2-(2-aminoethyl)benzimidazol-5-yl]-4,5-dihydro-5-methyl-3(2H)-pyridazinoneHCID 178517176HCID 178517176, compound

Product 1

HCID 178429555HCID 178429555, compound

Procedure

Prepared analogously to Example 1 from 1-(3,4-dihydro-2-hydroxy-quinolin-5-yloxy)-2,3-epoxypropane and 6-[2-(2-aminoethyl)benzimidazol-5-yl]-4,5-dihydro-5-methyl-3(2H)-pyridazinone.

Sources & evidence

ORD record
ord-d295cea6190048fe93efc7e3f293226b
Source dataset
uspto-grants-1992_08
Patent number
US05135932

Reaction notes

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