2-((4-(2-(Cyclopropylmethoxy)ethyl)phenoxy)methyl)oxirane → HCID 14884451, compound

HRID 846148Notes

Reaction equation

HRID 846148 reaction equation
[CH:1]1([CH2:4][O:5][CH2:6][CH2:7][C:8]2[CH:18]=[CH:17][C:11]([O:12][CH2:13][CH:14]3[O:16][CH2:15]3)=[CH:10][CH:9]=2)[CH2:3][CH2:2]1.[NH2:19][CH2:20][CH2:21][N:22]1[C:26]2[CH:27]=[CH:28][C:29]([C:31]3[CH2:32][CH2:33][C:34](=[O:37])[NH:35][N:36]=3)=[CH:30][C:25]=2[N:24]=[C:23]1[CH3:38]>>[CH:1]1([CH2:4][O:5][CH2:6][CH2:7][C:8]2[CH:18]=[CH:17][C:11]([O:12][CH2:13][CH:14]([OH:16])[CH2:15][NH:19][CH2:20][CH2:21][N:22]3[C:26]4[CH:27]=[CH:28][C:29]([C:31]5[CH2:32][CH2:33][C:34](=[O:37])[NH:35][N:36]=5)=[CH:30][C:25]=4[N:24]=[C:23]3[CH3:38])=[CH:10][CH:9]=2)[CH2:3][CH2:2]1

Participants

3

Reactant 2

HCID 117915422-((4-(2-(Cyclopropylmethoxy)ethyl)phenoxy)methyl)oxiraneHCID 15107859HCID 15107859, compound

Product 1

HCID 14884451HCID 14884451, compound

Procedure

Prepared analogously to Example 1 from 1-[4-(2-cyclopropylmethoxyethyl)phenoxy]-2,3-epoxypropane and 6-[1-(2-aminoethyl)-2-methyl-benzimidazol-5-yl]-4,5-dihydro-3(2H)pyridazinone.

Sources & evidence

ORD record
ord-de8c904274ca44b9ba206b9a8aff8c61
Source dataset
uspto-grants-1992_08
Patent number
US05135932

Reaction notes

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