1-[4-(2-Isobutoxyethyl)phenoxy]-2,3-epoxypropane → HCID 178450441, compound

HRID 846149Notes

Reaction equation

HRID 846149 reaction equation
[CH2:1]([O:5][CH2:6][CH2:7][C:8]1[CH:18]=[CH:17][C:11]([O:12][CH2:13][CH:14]2[O:16][CH2:15]2)=[CH:10][CH:9]=1)[CH:2]([CH3:4])[CH3:3].[NH2:19][CH2:20][CH2:21][N:22]1[C:26]2[CH:27]=[CH:28][C:29]([C:31]3[CH2:32][CH2:33][C:34](=[O:37])[NH:35][N:36]=3)=[CH:30][C:25]=2[N:24]=[C:23]1[OH:38]>>[CH2:1]([O:5][CH2:6][CH2:7][C:8]1[CH:18]=[CH:17][C:11]([O:12][CH2:13][CH:14]([OH:16])[CH2:15][NH:19][CH2:20][CH2:21][N:22]2[C:26]3[CH:27]=[CH:28][C:29]([C:31]4[CH2:32][CH2:33][C:34](=[O:37])[NH:35][N:36]=4)=[CH:30][C:25]=3[N:24]=[C:23]2[OH:38])=[CH:10][CH:9]=1)[CH:2]([CH3:4])[CH3:3]

Participants

3

Reactant 2

HCID 151078061-[4-(2-Isobutoxyethyl)phenoxy]-2,3-epoxypropaneHCID 178511321HCID 178511321, compound

Product 1

HCID 178450441HCID 178450441, compound

Procedure

Prepared analogously to Example 1 from 1-[4-(2- isobutoxy-ethyl)phenoxy]-2,3-epoxypropane and 6-[1-(2-aminoethyl)-2-hydroxy-benzimidazol-5-yl]-4,5-dihydro-3(2H)-pyridazinone.

Sources & evidence

ORD record
ord-4816727a51fe42a4ac739525c1e3d5cd
Source dataset
uspto-grants-1992_08
Patent number
US05135932

Reaction notes

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