2-({4-[2-(Cyclobutylmethoxy)ethyl]phenoxy}methyl)oxirane → HCID 14884411, compound

HRID 846161Notes

Reaction equation

HRID 846161 reaction equation
[CH:1]1([CH2:5][O:6][CH2:7][CH2:8][C:9]2[CH:19]=[CH:18][C:12]([O:13][CH2:14][CH:15]3[O:17][CH2:16]3)=[CH:11][CH:10]=2)[CH2:4][CH2:3][CH2:2]1.[NH2:20][CH2:21][CH2:22][C:23]1[CH:28]=[CH:27][C:26]([C:29]2[CH:30]=[CH:31][C:32](=[O:35])[NH:33][N:34]=2)=[CH:25][CH:24]=1>>[CH:1]1([CH2:5][O:6][CH2:7][CH2:8][C:9]2[CH:19]=[CH:18][C:12]([O:13][CH2:14][CH:15]([OH:17])[CH2:16][NH:20][CH2:21][CH2:22][C:23]3[CH:28]=[CH:27][C:26]([C:29]4[CH:30]=[CH:31][C:32](=[O:35])[NH:33][N:34]=4)=[CH:25][CH:24]=3)=[CH:11][CH:10]=2)[CH2:4][CH2:3][CH2:2]1

Participants

3

Reactant 2

HCID 151078052-({4-[2-(Cyclobutylmethoxy)ethyl]phenoxy}methyl)oxiraneHCID 15107871HCID 15107871, compound

Product 1

HCID 14884411HCID 14884411, compound

Procedure

Prepared analoqously to Example 1 from 1-[4-(2-cyclobutylmethoxyethyl)phenoxy]-2,3-epoxypropane and 6-[4-(2-aminoethyl)phenyl]-3(2H)-pyridazinone.

Sources & evidence

ORD record
ord-8632a6b87a5448c68d6fabc04f009437
Source dataset
uspto-grants-1992_08
Patent number
US05135932

Reaction notes

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