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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 846165Generated: October 31, 2026

1-[4-(2-Phenoxyethoxymethyl)phenoxy]-2,3-epoxypropane → 6-[4-[2-[3-(4-(2-Phenoxyethoxy-methyl)phenoxy)-2-hydroxypropylamino]ethoxy]-3-methyl-phenyl]-4,5-dihydro-3-(2H)-pyridazinone

https://huagongshe.com/reaction/846165

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-[4-(2-Phenoxyethoxymethyl)phenoxy]-2,3-epoxypropaneHCID 15107810—
Reactant6-[4-(2-aminoethoxy)-3-methyl-phenyl]-4,5-dihydro-3(2H)-pyridazinoneHCID 15107818—
Product6-[4-[2-[3-(4-(2-Phenoxyethoxy-methyl)phenoxy)-2-hydroxypropylamino]ethoxy]-3-methyl-phenyl]-4,5-dihydro-3-(2H)-pyridazinoneHCID 15107876—

Reaction Steps

Prepared analogously to Example 1 from 1-[4-(2-phenoxyethoxymethyl)phenoxy]-2,3-epoxypropane and 6-[4-(2-aminoethoxy)-3-methyl-phenyl]-4,5-dihydro-3-(2H)-pyridazinone.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05135932
Source datasetuspto-grants-1992_08
ORD IDord-9d84563de7524857950f398499f134b7
Source noteuspto-grants-1992_08