Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Methanol | HCID 887 | — |
| Reactant | Boron tribromide | HCID 25134 | — |
| Reactant | HCID 19884871 | HCID 19884871 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | HCID 19884867 | HCID 19884867 | — |
Reaction Steps
1,6-bis[2-(3,4-dimethoxybenzyl)pyrrolidin-1-yl]hexane was dissolved in dry CH2Cl2 and cooled to -70° C. under inert atmosphere. BBr3 was added. The mixture was warmed to room temperature and CH3OH was added. The solvent was removed in vacuo to give 1,6-bis-[2-(3,4-dihydroxybenzyl)pyrrolidin-1-yl]hexane.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US05135944 |
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| Source dataset | uspto-grants-1992_08 |
|---|
| ORD ID | ord-cf24988ea24340b1977c3126e46b4622 |
|---|
| Source note | uspto-grants-1992_08 |
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