HuagongsheHuagongshe Chemistry Print Report · For research reference only
2,3-Dihydroxybutanedioic Acid → HCID 19884951, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2,3-Dihydroxybutanedioic Acid | HCID 875 | — |
| Reactant | N,N-Dimethyl-3-(naphthalen-1-yloxy)-1-phenylpropan-1-amine | HCID 6093437 | — |
| Solvent | Ethanol | HCID 702 | — |
| Solvent | Water | HCID 962 | — |
| Product | HCID 19884951 | HCID 19884951 | 5.3% |
Reaction Steps
N,N-dimethyl-1-phenyl-3-(1-naphthalenyloxy)propanamine (32.44 g, 0.106 mol) was dissolved in 75 ml of ethanol and combined with 15.94 g (0.106 mol) of (+)-tartaric acid dissolved in 650 ml of water. The mixture was allowed to stand at room temperature overnight and the precipitated solid was vacuum filtered. The title compound (2.55 g) was isolated in enantiomerically pure form following seven recrystallizations from acetone. mp=94°-96° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05135947 |
| Source dataset | uspto-grants-1992_08 |
| ORD ID | ord-a358cccc7de04a65955c683a74643eb4 |
| Source note | uspto-grants-1992_08 |