反应详情

The compound of Example 29, (2.0 g, 4.197 mmoles) was suspended in chloroform (120 mls) to which was added 1,1-dichloromethylmethyl ether (10 ml). The reaction mixture was heated at 40° for 48 hours, and concentrated in vacuo. The residue was recrystallized to afford the title compound, m.p. 135°-136°.

1. temperatureThe reaction mixture was heated at 40° for 48 hours
2. concentrationconcentrated in vacuo
3. customThe residue was recrystallized