HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Chloro-4-fluorotoluene → 2,4-Diamino-5-(2-chloro-4-fluorophenyl)-6-methylpyrimidine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Chloro-4-fluorotoluene | HCID 96747 | — |
| Reactant | 2-Chloro-4-fluorophenylacetonitrile | HCID 2725063 | — |
| Reactant | 2,4-Diamino-5-(2,3-dichlorophenyl)-6-methylpyrimidine | HCID 11673419 | — |
| Product | 2,4-Diamino-5-(2-chloro-4-fluorophenyl)-6-methylpyrimidine | HCID 19705078 | — |
Reaction Steps
This compound was prepared in an analogous manner to the compound of Example 15 from 2-chloro-4-fluorophenylacetonitrile, which was itself prepared from 2-chloro-4-fluorotoluene (Aldrich, mp. 238° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05136080 |
| Source dataset | uspto-grants-1992_08 |
| ORD ID | ord-47351d6204a04d6490c0ea746025b57b |
| Source note | uspto-grants-1992_08 |