Methane → 3-[[6-Amino-2-[[3-(1-naphthalenyl)-2-(1-naphthalenylmethyl)-1-oxopropyl]amino]-1-oxohexyl]amino]-2-hydroxy-5-methylhexanoic acid, 1-methylethyl ester

Participants

Reaction Steps

[2R-[2R*,3S*(S*)]-2-hydroxy-5-methyl-3-[[2-[[3-(1-naphthalenyl)-2-(1-naphthalenylmethyl)-1-oxopropyl]amino]-1-oxo-6-[[(phenylmethoxy)carbonyl]amino]hexyl]amino]hexanoic acid, 1-methylethyl ester, 3.97 g (5.0 mmol), is dissolved in 250 ml of absolute ethanol, 0.5 g of 20% palladiun charcoal is added, and the mixture exposed to hydrogen gas for 18 hours. After complete uptake of hydrogen the mixture is filtered and concentrated to afford 3.44 g of the title compound.

Provenance & Evidence