Boron tribromide → HCID 19882794, compound

HRID 846512Notes

Reaction equation

HRID 846512 reaction equation
[Cl:1][C:2]1[CH:7]=[C:6]([Cl:8])[C:5]([O:9]C)=[CH:4][C:3]=1[N:11]1[C:15](=[O:16])[N:14]([CH2:17][CH3:18])[N:13]=[N:12]1.B(Br)(Br)Br>C(Cl)Cl>[Cl:1][C:2]1[CH:7]=[C:6]([Cl:8])[C:5]([OH:9])=[CH:4][C:3]=1[N:11]1[C:15](=[O:16])[N:14]([CH2:17][CH3:18])[N:13]=[N:12]1

Participants

4

Reactant 2

HCID 25134Boron tribromideHCID 14774809HCID 14774809, compound2×

Product 1

HCID 19882794HCID 19882794, compoundYield 84.1%

Reagents, catalysts & solvents 1

HCID 6344DichloromethaneSolvent

Procedure

In the manner of Example 11, Step A, the reaction of 1.56 g (0.0054 mole) of 1-(2,4-dichloro-5-methoxyphenyl)-1,4-dihydro-4-ethyl-5H-tetrazol-5-one (compound 7) and 4.06 g (0.016 mole) of boron tribromide in 20 mL of methylene chloride produced 1.25 g of 1-(2,4-dichloro-5-hydroxyphenyl)-1,4-dihydro-4-ethyl-5H-tetrazol-5-one, mp 149°-150° C.

Sources & evidence

ORD record
ord-fd87f0d3e45549039e629be29309c8e1
Source dataset
uspto-grants-1992_08
Patent number
US05136868

Reaction notes

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