HuagongsheHuagongshe Chemistry Print Report · For research reference only
Azidotrimethylsilane → 1-(2-chloro-4-fluoro-5-methoxyphenyl)-1,4-dihydro-5H-tetrazol-5-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Azidotrimethylsilane | HCID 78378 | — |
| Reactant | 2-Chloro-4-fluoro-5-methoxyphenyl isocyanate | HCID 19882833 | — |
| Product | 1-(2-chloro-4-fluoro-5-methoxyphenyl)-1,4-dihydro-5H-tetrazol-5-one | HCID 136160136 | 76.7% |
Reaction Steps
In the manner of Example 2, Step E, the reaction of 3.2 g (0.016 mole) of 2-chloro-4-fluoro-5-methoxyphenyl isocyanate with 3.2 g (0.028 mole) of trimethylsilyl azide produced 3.0 g of 1-(2-chloro-4-fluoro-5-methoxyphenyl)-1,4-dihydro-5H-tetrazol-5-one.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05136868 |
| Source dataset | uspto-grants-1992_08 |
| ORD ID | ord-abe9d8d67988493fbf7c2091574f4235 |
| Source note | uspto-grants-1992_08 |