Sodium Iodide → HCID 19883658, compound

Participants

Reaction Steps

1.32 g of 4-chloro-4'-(7-chloroheptyl)benzophenone and 0.85 g of sodium iodide were heated under reflux in 20 ml of ethyl methyl ketone. After 24 hours the reaction mixture was evaporated. The residue was suspended in 50 ml of water, whereupon the suspension was extracted three times with 50 ml of ethyl acetate each time, the combined organic phases were washed with 50 ml of a saturated sodium chloride solution, dried over magnesium sulphate and evaporated. There were obtained 1.5 g (90%) of crude 4-chloro-4'-(7-iodoheptyl)benzophenone as a yellowish oil which was used in the next step without further purification.

Provenance & Evidence