HCID 19883511, compound → HCID 19883537, compound

Participants

Reaction Steps

A mixture of 13.5 parts of N,N-diethyl-2-[[4,4-dimethoxy-1(phenylmethyl)-3-piperidinyl]oxy]ethanamine and 120 parts of methanol was hydrogenated at normal pressure and at room temperature with 2 parts of palladium-on-charcoal catalyst 10%. After the calculated amount of hydrogen was taken up, the catalyst was filtered off and the filtrate was evaporated, yielding 10.5 parts (100%) of N,N-diethyl-2-[(4,4-dimethoxy-3-piperidinyl)oxy]ethanamine as a residue (intermediate 109).

Provenance & Evidence