Water → N-[2,4-Diisopropyl-5-methoxymethyl-benzal]-phenylamine

Participants

Reaction Steps

A solution of 10.36 g (44.3 mmol) of the compound from Example 5, 4.06 g (44.6 mmol) of freshly distilled aniline and 0.3 g of p-toluenesulphonic acid in 370 ml of toluene is heated under reflux for 1.5 h in a water separator (molecular sieve 4 Å), diluted with ethyl acetate after cooling to room temperature, washed with saturated sodium hydrogencarbonate solution and water, dried using sodium sulphate and concentrated in vacuo.

Provenance & Evidence