HCID 178429728, compound → HCID 178429727, compound

HRID 846903Notes

Reaction equation

HRID 846903 reaction equation
[SH:1][C:2]1[CH:7]=[C:6]([CH3:8])[N:5]2[N:9]=[CH:10][C:11](C(O)=O)=[C:4]2[N:3]=1>C(=O)([O-])O.[K+]>[CH3:8][C:6]1[N:5]2[N:9]=[CH:10][CH:11]=[C:4]2[N:3]=[C:2]([SH:1])[CH:7]=1

Participants

3

Reactant 1

HCID 178429728HCID 178429728, compound

Product 1

HCID 178429727HCID 178429727, compound

Reagents, catalysts & solvents 1

HCID 516893Potassium BicarbonateSolvent

Procedure

2.00 g of 5-mercapto-7-methylpyrazolo[1,5-a]pyrimidine-3-carboxylic acid were heated to 220° under argon for 1 hour. After cooling, the reaction mixture was taken up in 10 percent potassium hydrogen carbonate solution. The insoluble portion was filtered off under suction and taken up in water. The solution was acidified to pH 2 and the precipitate was filtered off under suction. After drying, there was obtained 7-methylpyrazolo[1,5-a]pyrimidine-5-thiol.

Workup

  1. temperatureAfter cooling
  2. filtrationThe insoluble portion was filtered off under suction
  3. filtrationthe precipitate was filtered off under suction
  4. customAfter drying

Sources & evidence

ORD record
ord-aa36ea2948644703b590c68ebbc1c383
Source dataset
uspto-grants-1992_08
Patent number
US05138066

Reaction notes

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