1-Hexadecylthio-3-trityloxy-2-propanol → 1-Hexadecylthio-3-(3-iodopropylsulfonylamino)-2-methylcarbamoyloxypropane

HRID 846978Notes

Reaction equation

HRID 846978 reaction equation
ClCCCCS(NCC(OC)C[O:13][C:14](=O)[NH:15][CH2:16]CCCCCCCCCCCCCCCCC)(=O)=O.[CH2:37]([S:53][CH2:54][CH:55]([OH:77])[CH2:56]OC(C1C=CC=CC=1)(C1C=CC=CC=1)C1C=CC=CC=1)[CH2:38][CH2:39][CH2:40][CH2:41][CH2:42][CH2:43][CH2:44][CH2:45][CH2:46][CH2:47][CH2:48][CH2:49][CH2:50][CH2:51][CH3:52].C(SCC(OC)C[NH:98][S:99]([CH2:102][CH2:103][CH2:104][I:105])(=[O:101])=[O:100])CCCCCCCCCCCCCCC>>[CH2:37]([S:53][CH2:54][CH:55]([O:77][C:14](=[O:13])[NH:15][CH3:16])[CH2:56][NH:98][S:99]([CH2:102][CH2:103][CH2:104][I:105])(=[O:100])=[O:101])[CH2:38][CH2:39][CH2:40][CH2:41][CH2:42][CH2:43][CH2:44][CH2:45][CH2:46][CH2:47][CH2:48][CH2:49][CH2:50][CH2:51][CH3:52]

Participants

4

Reactant 3

HCID 130028641-Hexadecylthio-3-trityloxy-2-propanolHCID 148350231-Hexadecylthio-3-(3-iodopropylsulfonylamino)-2-methoxypropaneHCID 148350313-(4-Chlorobutylsulfonylamino)-2-methoxy-1-octadecylcarbamoyloxypropane

Product 1

HCID 540820441-Hexadecylthio-3-(3-iodopropylsulfonylamino)-2-methylcarbamoyloxypropane

Procedure

3-(3-Chloropropylsulfonylamino)-1-hexadecylthio-2-methylcarbamoyloxypropan III c1 is allowed to react and worked up by the same procedure as described in (5). The summary of the experimental condition and the physical data of the product are listed in the Table 8.

Workup

  1. customto react

Sources & evidence

ORD record
ord-4079d55b994d46cbab4cae46c5b8f31b
Source dataset
uspto-grants-1992_08
Patent number
US05138067

Reaction notes

Loading…