2-Methylcarbamoyloxy-3-octadecylcarbamoyloxypropanol → HCID 14834997, compound
Reaction equation
CN[C:3]([O:5][CH:6]([CH2:9][O:10][C:11](=[O:31])[NH:12][CH2:13][CH2:14][CH2:15][CH2:16][CH2:17][CH2:18][CH2:19][CH2:20][CH2:21][CH2:22][CH2:23][CH2:24][CH2:25][CH2:26][CH2:27][CH2:28][CH2:29][CH3:30])[CH2:7]O)=O.[CH2:32]([S:48][CH2:49][CH:50]([O:72][C:73](=[O:76])[NH:74][CH3:75])[CH2:51][O:52][C:53]([C:66]1[CH:71]=[CH:70][CH:69]=[CH:68][CH:67]=1)([C:60]1[CH:65]=[CH:64][CH:63]=[CH:62][CH:61]=1)[C:54]1[CH:59]=[CH:58][CH:57]=[CH:56][CH:55]=1)[CH2:33][CH2:34][CH2:35][CH2:36][CH2:37][CH2:38][CH2:39][CH2:40][CH2:41][CH2:42][CH2:43][CH2:44][CH2:45][CH2:46][CH3:47].[CH2:77](SCC(OC)CN)CCCCCCCCCCCCCCC>>[NH2:74][CH2:73][C:6]1([CH2:9][O:10][C:11](=[O:31])[NH:12][CH2:13][CH2:14][CH2:15][CH2:16][CH2:17][CH2:18][CH2:19][CH2:20][CH2:21][CH2:22][CH2:23][CH2:24][CH2:25][CH2:26][CH2:27][CH2:28][CH2:29][CH3:30])[CH2:7][CH2:77][CH2:3][O:5]1.[CH2:32]([S:48][CH2:49][CH:50]([O:72][C:73](=[O:76])[NH:74][CH3:75])[CH2:51][O:52][C:53]([C:66]1[CH:71]=[CH:70][CH:69]=[CH:68][CH:67]=1)([C:60]1[CH:61]=[CH:62][CH:63]=[CH:64][CH:65]=1)[C:54]1[CH:55]=[CH:56][CH:57]=[CH:58][CH:59]=1)[CH2:33][CH2:34][CH2:35][CH2:36][CH2:37][CH2:38][CH2:39][CH2:40][CH2:41][CH2:42][CH2:43][CH2:44][CH2:45][CH2:46][CH3:47]Participants
5
Procedure
2-Methylcarbamoyloxy-3-octadecylcarbamoyloxypropanol V c2 is allowed to react and worked up by the same procedure as described in (3) to give an amine IV c2 of m.p. 91°-92° C. The summary of the experimental condition and the physical data of the product are listed in the Table 5 and 6.
Workup
- customto react
Sources & evidence
- ORD record
- ord-bfcc40b548ac451590bc48965ab879c5
- Source dataset
- uspto-grants-1992_08
- Patent number
- US05138067
Reaction notes
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