2-Methylcarbamoyloxy-3-octadecylcarbamoyloxypropylamine → 3-(3-Chloropropylsulfonylamino)-2-methoxycarbonylamino-1-octadecylcarbamoyloxypropane

HRID 846985Notes

Reaction equation

HRID 846985 reaction equation
CNC(O[CH:6]([CH2:9][O:10][C:11](=[O:31])[NH:12][CH2:13][CH2:14][CH2:15][CH2:16][CH2:17][CH2:18][CH2:19][CH2:20][CH2:21][CH2:22][CH2:23][CH2:24][CH2:25][CH2:26][CH2:27][CH2:28][CH2:29][CH3:30])[CH2:7][NH2:8])=O.[Cl:32][CH2:33][CH2:34][CH2:35][S:36](NCC(OC)CSCCCCCCCCCCCCCCCC)(=[O:38])=[O:37]>>[Cl:32][CH2:33][CH2:34][CH2:35][S:36]([NH:8][CH2:7][CH:6]([NH:12][C:11]([O:10][CH3:9])=[O:31])[CH2:9][O:10][C:11](=[O:31])[NH:12][CH2:13][CH2:14][CH2:15][CH2:16][CH2:17][CH2:18][CH2:19][CH2:20][CH2:21][CH2:22][CH2:23][CH2:24][CH2:25][CH2:26][CH2:27][CH2:28][CH2:29][CH3:30])(=[O:37])=[O:38]

Participants

3

Reactant 2

HCID 148349992-Methylcarbamoyloxy-3-octadecylcarbamoyloxypropylamineHCID 14835022HCID 14835022, compound

Product 1

HCID 148350403-(3-Chloropropylsulfonylamino)-2-methoxycarbonylamino-1-octadecylcarbamoyloxypropane

Procedure

2-Methoxycarbonylamino-3-octadecylcarbamoyloxypropylamine IV e1 is allowed to react and worked up by the same procedure as described in (4). mp. 99°-101° C. The summary of the experimental condition and the physical data of the product are listed in Table 7.

Workup

  1. customto react

Sources & evidence

ORD record
ord-026eba8677fe4efcb450de27065ddfcc
Source dataset
uspto-grants-1992_08
Patent number
US05138067

Reaction notes

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