1-Hexadecylthio-3-(3-iodopropylsulfonylamino)-2-methoxypropane → 2-Butoxycarbonylamino-1-hexadecylthio-3-(3-iodopropylsulfonylamino)propane

HRID 846990Notes

Reaction equation

HRID 846990 reaction equation
[CH2:1]([O:5][C:6]([NH:8]C(CNS(CCCCl)(=O)=O)COC(=O)NCCCCCCCCCCCCCCCCCC)=[O:7])[CH2:2][CH2:3][CH3:4].[CH2:42]([S:58][CH2:59][CH:60](OC)[CH2:61][NH:62][S:63]([CH2:66][CH2:67][CH2:68][I:69])(=[O:65])=[O:64])[CH2:43][CH2:44][CH2:45][CH2:46][CH2:47][CH2:48][CH2:49][CH2:50][CH2:51][CH2:52][CH2:53][CH2:54][CH2:55][CH2:56][CH3:57]>>[CH2:1]([O:5][C:6]([NH:8][CH:60]([CH2:61][NH:62][S:63]([CH2:66][CH2:67][CH2:68][I:69])(=[O:64])=[O:65])[CH2:59][S:58][CH2:42][CH2:43][CH2:44][CH2:45][CH2:46][CH2:47][CH2:48][CH2:49][CH2:50][CH2:51][CH2:52][CH2:53][CH2:54][CH2:55][CH2:56][CH3:57])=[O:7])[CH2:2][CH2:3][CH3:4]

Participants

3

Reactant 2

HCID 148350231-Hexadecylthio-3-(3-iodopropylsulfonylamino)-2-methoxypropaneHCID 19884242HCID 19884242, compound

Product 1

HCID 198842472-Butoxycarbonylamino-1-hexadecylthio-3-(3-iodopropylsulfonylamino)propane

Procedure

2-Butoxycarbonylamino-3-(3-chloropropylsulfonylamino)-1-hexadecylthiopropane III e4 is allowed to react and worked up by the same procedure as described in (5). m.p. 82°-83° C. The summary of the experimental condition and the physical data of the product are listed in Table 8.

Workup

  1. customto react

Sources & evidence

ORD record
ord-8f26ccd6b28b4f5e9190a5431cf5b1b5
Source dataset
uspto-grants-1992_08
Patent number
US05138067

Reaction notes

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