HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium Hydroxide → 2-(2-Benzoyloxypropan-1-yl)-3-hexadecylthiopropanol
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium Hydroxide | HCID 14798 | — |
| Reactant | 2-(2-Benzoyloxypropan-1-yl)-3-hexadecylthiopropyl benzoate | HCID 53917600 | — |
| Solvent | Methanol | HCID 887 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | 2-(2-Benzoyloxypropan-1-yl)-3-hexadecylthiopropanol | HCID 14834992 | 62.8% |
Reaction Steps
Using 6.89 ml (13.78 mM) of 2N aqueous sodium hydroxide, 4.017 g (6.89 mM) of 2-(2-benzoyloxypropan-1-yl)-3-hexadecylthio-propyl benzoate m11 in 38 ml of methanol and 43 ml of tetrahydrofuran is converted to 2.071 g (62.8% yield) of the titled compound m12 by the same procedure as described in (125).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05138067 |
| Source dataset | uspto-grants-1992_08 |
| ORD ID | ord-b1aabedd133c416b92bcf040d94ec06f |
| Source note | uspto-grants-1992_08 |