反应详情

Following Example 70 and General Procedure D, 8-bromo-N-(2,4-difluorophenyl)-N-methyl-4H-thieno[3,2-c]chromene-2-carboxamide 160bp and morpholine were reacted to give 129bp. 1H NMR (400 MHz, CDCl3) δ: 7.27 (m, 1 H), 7.11-7.14 (m, 2 H), 6.90-6.98 (m, 3 H), 6.75 (s, 1 H), 5.09 (s, 2 H), 4.04 (m, 2 H), 3.38 (s, 3 H), 3.32 (m, 2 H). LCMS (ESI) m/z: 442.9

1. customwere reacted
2. customto give 129bp