HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-tert-Butoxycarbonylamino-3-octadecylcarbamoyloxypropylamine → 2-Cyanomethyl-3-hexadecyloxypropylamine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-tert-Butoxycarbonylamino-3-octadecylcarbamoyloxypropylamine | HCID 14835001 | — |
| Reactant | 2-(2-Benzoyloxypropan-1-yl)-3-octadecylcarbamoyloxypropylamine | HCID 14835012 | — |
| Reactant | 1-Azido-2-cyanomethyl-3-hexadecyloxypropane | HCID 19884208 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | 2-Cyanomethyl-3-hexadecyloxypropylamine | HCID 14835013 | — |
Reaction Steps
A suspension of 3.00 g (23 mM) of 1-azido-2-cyanomethyl-3-hexadecyloxypropane V n1b and 300 mg of 10% palladium on charcoal in 100 ml of methanol is hydrogenated as described in (129) and the crude product of the titled compound IV n1 is obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05138067 |
| Source dataset | uspto-grants-1992_08 |
| ORD ID | ord-3b6c824d548a4842877ca522fc6c3286 |
| Source note | uspto-grants-1992_08 |