HuagongsheHuagongshe Chemistry Print Report · For research reference only
Triethylamine → 2-(2-Benzoyloxypropan-1-yl)-3-hexadecylthiopropanol methanesulfonate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Triethylamine | HCID 8471 | — |
| Reactant | Methanesulfonyl chloride | HCID 31297 | — |
| Reactant | 2-(2-Benzoyloxypropan-1-yl)-3-hexadecylthiopropanol | HCID 14834992 | — |
| Reactant | 3-Azido-1-hexadecylthio-2-methoxycarbonylaminopropane | HCID 14835094 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | 2-(2-Benzoyloxypropan-1-yl)-3-hexadecylthiopropanol methanesulfonate | HCID 53635267 | — |
Reaction Steps
A mixture of 1.268 g (2.65 mM) of 2-(2-benzoyloxypropan-1-yl)-3-n-hexadecylthiopropanol m12, 0.270 ml (3.45 mM) of methanesulfonyl chloride and 0.56 ml (3.98 mM) of triethylamine in 30 ml of dichloromethane is allowed to react by the same procedure as described in (52) and the crude product of the titled compound m12a is obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05138067 |
| Source dataset | uspto-grants-1992_08 |
| ORD ID | ord-3aae12392bd7453ba6af22281baad0ba |
| Source note | uspto-grants-1992_08 |