HCID 19815383, compound → HCID 178494082, compound

HRID 847034Notes

Reaction equation

HRID 847034 reaction equation
[OH:1][CH2:2][C:3]1[N:7](CC2C=CC([N+]([O-])=O)=CC=2)[C:6]([O:18][CH3:19])=[N:5][CH:4]=1.[C:20]([C:23]1[CH:47]=[CH:46][CH:45]=[CH:44][C:24]=1[C:25]([NH:27][C:28]1[CH:43]=[CH:42][C:31]([CH2:32]N2C(CO)=CN=C2OC)=[CH:30][CH:29]=1)=[O:26])([OH:22])=[O:21]>>[C:20]([C:23]1[CH:47]=[CH:46][CH:45]=[CH:44][C:24]=1[C:25]([NH:27][C:28]1[CH:29]=[CH:30][C:31]([CH2:32][C:4]2[N:5]=[C:6]([O:18][CH3:19])[NH:7][C:3]=2[CH2:2][OH:1])=[CH:42][CH:43]=1)=[O:26])([OH:22])=[O:21]

Participants

3

Reactant 2

HCID 19815383HCID 19815383, compoundHCID 19815393HCID 19815393, compound

Product 1

HCID 178494082HCID 178494082, compound

Procedure

By repeating Example 72, Parts C and D, but substituting 5-hydroxymethyl-2-methoxy-1-(4-nitrobenzyl)imidazole as starting material in Part C, the compound 1-[4-(2-carboxybenzamido)benzyl]-5-hydroxymethyl-2-methoxyimidazole can be prepared.

Sources & evidence

ORD record
ord-3fc7d927c7434523a1e7c942aca0bb94
Source dataset
uspto-grants-1992_08
Patent number
US05138069

Reaction notes

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