m-Chloroperbenzoic acid → HCID 178527108, compound

Participants

Reaction Conditions

Reaction Steps

To a solution of 2-(2-phenylethyl)-1,3,2-benzodithiazole (0.538 g, 2.08 mmol), from Step 2, in 30 mL of chloroform at -20° C., was added portionwise 56% meta-chloroperoxybenzoic acid (mCPBA) (0.64 g, 2 mmol). The reaction mixture was allowed to warm to 0° C. over a 2 hour period and then the reaction was quenched at 10° C. with 20 mL of 1M aqueous sodium bicarbonate solution. The organic layer was concentrated in vacuo and the residue was purified by column chromatography on silica gel eluting with chloroform (CHCl3) to give 389 mg (65.7% yield) of the title compound. Analysis calculated for C14H13NOS2 : C, 61.08; H, 4.76; N, 5.09. Found: C, 60.92; H, 4.75; N, 5.04.

Provenance & Evidence