HCID 9875381, compound → HCID 19882361, compound

HRID 847152Notes

Reaction equation

HRID 847152 reaction equation
[N+:1]([C:4]1[CH:9]=[CH:8][C:7]([S:10]([CH2:21][CH2:22][CH2:23][O:24][C:25]2[CH:30]=[CH:29][CH:28]=[CH:27][CH:26]=2)(=[N:12][CH2:13][CH2:14][N:15]2[CH2:20][CH2:19][O:18][CH2:17][CH2:16]2)=[O:11])=[CH:6][CH:5]=1)([O-])=O>C(O)C.[Pd]>[N:15]1([CH2:14][CH2:13][N:12]=[S:10]([C:7]2[CH:6]=[CH:5][C:4]([NH2:1])=[CH:9][CH:8]=2)([CH2:21][CH2:22][CH2:23][O:24][C:25]2[CH:30]=[CH:29][CH:28]=[CH:27][CH:26]=2)=[O:11])[CH2:20][CH2:19][O:18][CH2:17][CH2:16]1

Participants

4

Reactant 1

HCID 9875381HCID 9875381, compound

Product 1

HCID 19882361HCID 19882361, compound

Reagents, catalysts & solvents 2

HCID 23938PalladiumCatalystHCID 702EthanolSolvent

Procedure

A solution of S-(4-nitrophenyl)-S-(3-phenoxypropyl)-N-[2-(4-morpholinyl)ethyl]sulfoximine in ethanol is treated with 5% palladium on carbon catalyst and subjected to hydrogenation on a Parr apparatus. When hydrogen uptake ceases, the catalyst is removed by filtration and the filtrate is concentrated to obtain the title compound.

Workup

  1. customWhen hydrogen uptake ceases, the catalyst is removed by filtration
  2. concentrationthe filtrate is concentrated

Sources & evidence

ORD record
ord-644b8106c4ea40338b5b17d316d215ab
Source dataset
uspto-grants-1992_08
Patent number
US05140026

Reaction notes

Loading…