HuagongsheHuagongshe Chemistry Print Report · For research reference only
1,2-Dichloroethane → HCID 19882549, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1,2-Dichloroethane | HCID 11 | — |
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Reactant | 5,6-Dihydroxy-3,4-dihydronaphthalen-1(2H)-one | HCID 12353640 | — |
| Solvent | Dimethyl Sulfoxide | HCID 679 | — |
| Product | HCID 19882549 | HCID 19882549 | — |
Reaction Steps
5,6-Dihydroxy-1-tetralone (6 g) was heated at 125° C. with 1,2-dichloroethane (7 ml) and K2CO3 (14 g) in DMSO (70 ml) under N2 for 45 min. The reaction was quenched with ice water then extracted with Et2O. The aqueous layer was removed, then EtOAc added to the remaining organics. This solution was dried (MgSO4), filtered and evaporated to give the desired product.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05140040 |
| Source dataset | uspto-grants-1992_08 |
| ORD ID | ord-4828b4d186554648ac9f5712d539e94e |
| Source note | uspto-grants-1992_08 |