Fenoterol hydrobromide → Fenoterol

HRID 847342Notes

Reaction equation

HRID 847342 reaction equation
[CH3:1][CH:2]([NH:11][CH2:12][CH:13]([OH:22])[C:14]1[CH:15]=[C:16]([OH:21])[CH:17]=[C:18]([OH:20])[CH:19]=1)[CH2:3][C:4]1[CH:5]=[CH:6][C:7]([OH:10])=[CH:8][CH:9]=1.Br>C(Cl)(Cl)(Cl)F>[CH3:1][CH:2]([NH:11][CH2:12][CH:13]([OH:22])[C:14]1[CH:19]=[C:18]([OH:20])[CH:17]=[C:16]([OH:21])[CH:15]=1)[CH2:3][C:4]1[CH:9]=[CH:8][C:7]([OH:10])=[CH:6][CH:5]=1

Participants

3

Reactant 1

HCID 5702161Fenoterol hydrobromide

Product 1

HCID 3343Fenoterol

Reagents, catalysts & solvents 1

HCID 6389TrichlorofluoromethaneSolvent2×

Procedure

50 mg of micronised fenoterol HBr was dispersed uniformly in a solution of soy-bean lecithin (600 mg) 95% pure in 2 g of Arcton 11. The Arcton 11 was allowed to flash off, leaving behind a dispersion of fenoterol particles in lipid. To this dispersion, 5 g of micronised lactose was added. The resultant powder composition was tumbled in a ball-mill to ensure uniform mixing.

Sources & evidence

ORD record
ord-c0ac4975696a4e16868584b873a6a7ad
Source dataset
uspto-grants-1992_08
Patent number
US05141674

Reaction notes

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