Hydrochloric Acid → HCID 19881348, compound

Participants

Reaction Steps

To a suspension of 20.1 g (0.05 mol) diselenosalicylic acid in 20 ml water is added 15.0 g (0.375 mol) sodium hydroxide in one portion with stirring. After dissolution 39.75 g (0.375 mol) sodium carbonate and 23.9 g (0.1375 mol) sodium dithionite are added and the mixture is heated to reflux for 2 h, allowed to cool to room temperature and 30.1 g (0.1625 mol) 4-methylbenzyl bromide in 125 ml ethanol is added dropwise within 15 minutes, followed by stirring overnight. The reaction mixture is acidified under stirring with 150 ml aqueous hydrochloric acid (32%), the white precipitate is filtered off, washed with 200 ml water and dried. The residue is purified by recrystallization from ethyl acetate.

Provenance & Evidence