HuagongsheHuagongshe Chemistry Print Report · For research reference only
Acetyl chloride → N-[(1S,2S)-2-Hydroxycyclopentyl]acetamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Acetyl chloride | HCID 6367 | — |
| Reactant | (1S,2S)-2-Aminocyclopentanol | HCID 11571787 | — |
| Product | N-[(1S,2S)-2-Hydroxycyclopentyl]acetamide | HCID 14988810 | — |
Reaction Steps
Following the procedure of Example 2A, 74.7 g of (S,S)-(+)-2-aminocyclopentanol were reacted with acetyl chloride to provide 107.9 g of the title intermediate as an oil which crystallized upon cooling. NMR.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05141944 |
| Source dataset | uspto-grants-1992_08 |
| ORD ID | ord-6aba970c2007456bb928291ced9816a0 |
| Source note | uspto-grants-1992_08 |