7-Amino-3-(4,6-diamino-1-ethylpyrimidinium-2-yl)thiomethyl-3-cephem-4-carboxylate → 7-Amino-3-(4,6-diamino-1-methyl-pyrimidinium-2-yl)thiomethyl-3-cephem-4-carboxylate

HRID 847422Notes

Reaction equation

HRID 847422 reaction equation
[NH2:1][CH:2]1[C:24](=[O:25])[N:4]2[C:5]([C:21]([O-:23])=[O:22])=[C:6]([CH2:9][S:10][C:11]3[N:16]=[C:15]([NH2:17])[CH:14]=[C:13]([NH2:18])[N+:12]=3[CH2:19]C)[CH2:7][S:8][C@H:3]12.NC1C(=O)N2C(C([O-])=O)=C(CSC3N=C(N)C=C(N)[N+]=3N)CS[C@H]12.NC1C(=O)N2C(C([O-])=O)=C(CSC3N=C(N)C(C)=C(N)[N+]=3C)CS[C@H]12.NC1C(=O)N2C(C([O-])=O)=C(CSC3N=C(N)C(C)=C(N)[N+]=3N)CS[C@H]12>>[NH2:1][CH:2]1[C:24](=[O:25])[N:4]2[C:5]([C:21]([O-:23])=[O:22])=[C:6]([CH2:9][S:10][C:11]3[N:16]=[C:15]([NH2:17])[CH:14]=[C:13]([NH2:18])[N+:12]=3[CH3:19])[CH2:7][S:8][C@H:3]12

Participants

5

Reactant 4

HCID 677876667-Amino-3-(4,6-diamino-1-ethylpyrimidinium-2-yl)thiomethyl-3-cephem-4-carboxylateHCID 677879807-Amino-3-(1,4,6-triaminopyrimidinium-2-yl)thiomethyl-3-cephem-4-carboxylateHCID 677884847-Amino-3-(5-methyl-1,4,6-triaminopyrimidinium-2-yl)thiomethyl-3-cephem-4-carboxylateHCID 677886717-Amino-3-(4,6-diamino-1,5-dimethyl-pyrimidinium-2-yl)thiomethyl-3-cephem-4-carboxylate

Product 1

HCID 677883687-Amino-3-(4,6-diamino-1-methyl-pyrimidinium-2-yl)thiomethyl-3-cephem-4-carboxylate

Procedure

7-amino-3-(4,6-diamino-1-ethylpyrimidinium-2-yl)thiomethyl-3-cephem-4-carboxylate; 7-amino-3-(1,4,6-triaminopyrimidinium-2-yl)thiomethyl-3-cephem-4-carboxylate; 7-amino-3-(4,6-diamino-1,5-dimethylpyrimidinium-2-yl)thiomethyl-3-cephem-4-carboxylate; and 7-amino-3-(5-methyl-1,4,6-triaminopyrimidinium-2-yl)thiomethyl-3-cephem-4-carboxylate.

Sources & evidence

ORD record
ord-a6cc5e04855c469c90411be81bde29dc
Source dataset
uspto-grants-1992_08
Patent number
US05142041

Reaction notes

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