Benzenepropanal → HCID 14249550, compound

HRID 847597Notes

Reaction equation

HRID 847597 reaction equation
Br[C:2]([F:9])([F:8])[C:3]([O:5][CH2:6][CH3:7])=[O:4].[CH:10](=[O:19])[CH2:11][CH2:12][C:13]1[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=1>>[F:8][C:2]([F:9])([CH:10]([OH:19])[CH2:11][CH2:12][C:13]1[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=1)[C:3]([O:5][CH2:6][CH3:7])=[O:4]

Participants

3

Reactant 2

HCID 7707BenzenepropanalHCID 69585Ethyl bromodifluoroacetate

Product 1

HCID 14249550HCID 14249550, compound

Procedure

According to the procedure of Thaisrivongs et. al. (J. Med. Chem., 1986, 29, 2080), ethyl bromodifluoroacetate was condensed with hydrocinnamaldehyde to give the desired compound.

Sources & evidence

ORD record
ord-9a3bf19be9cd4f159d89e7ae911084c4
Source dataset
uspto-grants-1992_08
Patent number
US05142056

Reaction notes

Loading…