Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 847619Generated: October 26, 2026

Benzenepropanoic acid, alpha-(phenylmethyl)- → 2(t-Butyloxycarbonylamino)-4-(N-(3-phenyl-2-(phenylmethyl)propionyl)amino)-1,5-diphenyl-3-hydroxypentane

https://huagongshe.com/reaction/847619

Reaction equation

Participants

RoleNameHCIDCharge
ReactantBenzenepropanoic acid, alpha-(phenylmethyl)-HCID 64800—
ReactantCarbodiimideHCID 160435—
Reactant4-Amino-2-(t-butyloxycarbonylamino)-1,5-diphenyl-3-hydroxypentaneHCID 14704377—
Product2(t-Butyloxycarbonylamino)-4-(N-(3-phenyl-2-(phenylmethyl)propionyl)amino)-1,5-diphenyl-3-hydroxypentaneHCID 19431018—

Reaction Steps

According to the carbodiimide coupling procedure of Example 55, dibenzylacetic acid was coupled to the resultant compound of Example 11 to give the desired compound.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05142056
Source datasetuspto-grants-1992_08
ORD IDord-4be0d3df400b495986d9b3f3176c6910
Source noteuspto-grants-1992_08