Carbodiimide → HCID 22864440, compound

HRID 847621Notes

Reaction equation

N=[C:2]=[NH:3].Cl.Cl.[NH2:6][CH:7]([CH:15]([OH:43])[CH:16]([NH:24][C:25](=[O:42])[C@H:26]([CH:39]([CH3:41])[CH3:40])[NH:27][S:28](=[O:38])(=[O:37])[NH:29][N:30]1[CH2:35][CH2:34][N:33]([CH3:36])[CH2:32][CH2:31]1)[CH2:17][C:18]1[CH:23]=[CH:22][CH:21]=[CH:20][CH:19]=1)[CH2:8][C:9]1[CH:14]=[CH:13][CH:12]=[CH:11][CH:10]=1>>[CH3:36][N:33]1[CH2:32][CH2:31][N:30]([NH:29][S:28]([NH:27][C@H:26]([C:25]([NH:24][CH:16]([CH:15]([OH:43])[CH:7]([NH:6][C:25](=[O:42])[C@H:26]([CH:39]([CH3:40])[CH3:41])[NH:27][S:28](=[O:37])(=[O:38])[NH:29][N:30]2[CH2:31][CH2:32][N:3]([CH3:2])[CH2:34][CH2:35]2)[CH2:8][C:9]2[CH:10]=[CH:11][CH:12]=[CH:13][CH:14]=2)[CH2:17][C:18]2[CH:19]=[CH:20][CH:21]=[CH:22][CH:23]=2)=[O:42])[CH:39]([CH3:41])[CH3:40])(=[O:37])=[O:38])[CH2:35][CH2:34]1

Participants

Reactant 2

HCID 160435Carbodiimide

HCID 22864447HCID 22864447, compound

Product 1

HCID 22864440HCID 22864440, compound

Procedure

According to the carbodiimide coupling procedure of Example 55, the resultant compound of Example 137B was coupled to the resultant compound of Example 138 to give the desired compound.

Sources & evidence

ORD record: ord-ff5d7a730cc6432e9f1e21fb2ae6a9e8
Source dataset: uspto-grants-1992_08
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US05142056

Reaction notes

Loading…