Diethylphosphite → HCID 20566751, compound

HRID 847674Notes

Reaction equation

[CH2:1]([N:4]([CH2:12][CH3:13])[S:5]([C:8]([F:11])([F:10])[F:9])(=[O:7])=[O:6])[CH:2]=[CH2:3].[CH2:14]([O:16][P:17]([O-:21])[O:18][CH2:19][CH3:20])[CH3:15]>>[CH2:12]([N:4]([CH2:1][CH2:2][CH2:3][P:17]([O:18][CH2:19][CH3:20])(=[O:21])[O:16][CH2:14][CH3:15])[S:5]([C:8]([F:11])([F:9])[F:10])(=[O:7])=[O:6])[CH3:13]

Participants

Reactant 2

HCID 3780918Diethylphosphite

HCID 20566758HCID 20566758, compound

Product 1

HCID 20566751HCID 20566751, compound

Procedure

Following the procedure of Example 1, N-allyl-N-ethyltrifluoromethanesulfonamide (b.p. 395° C. at 1.50-0.35 torr) was reacted with diethylphosphite to produce diethyl 3-(N-ethyltrifluoromethanesulfonamido)propanephosphonate (b.p. 147°-155° C. at 0.25 torr). Following the procedure of Example 2, this phosphonate was hydrolyzed to produce the corresponding phosphonic acid (m.p. 137.5°-139.5° C.).

Sources & evidence

ORD record: ord-151b77b8404b4faa9a7f8a03eb6556b9
Source dataset: uspto-grants-1981_10
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US04293441

Reaction notes

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