Malonic Acid → 2-Acetylbenzoic acid

HRID 847708Notes

Reaction equation

HRID 847708 reaction equation
[C:1]1(=[O:11])[O:6][C:4](=[O:5])[C:3]2=[CH:7][CH:8]=[CH:9][CH:10]=[C:2]12.[C:12](O)(=O)CC(O)=O>N1C=CC=CC=1>[C:4]([C:3]1[CH:7]=[CH:8][CH:9]=[CH:10][C:2]=1[C:1]([OH:6])=[O:11])(=[O:5])[CH3:12]

Participants

4

Reactant 2

HCID 867Malonic AcidHCID 6811Phthalic Anhydride

Product 1

HCID 684742-Acetylbenzoic acid

Reagents, catalysts & solvents 1

HCID 1049PyridineSolvent

Procedure

Heating at 80° to 85° C. of the phthalic anhydride (5) derived from (1) with malonic acid in pyridine affords the o-acetylbenzoic acid (6). ##STR15##

Sources & evidence

ORD record
ord-85c6152fbef1433fa868237e45b284fe
Source dataset
uspto-grants-1981_10
Patent number
US04293553

Reaction notes

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