Hydrochloric Acid → 1-Propanone, 3-(1H-imidazol-1-yl)-1-(2-naphthalenyl)-, monohydrochloride

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Reaction Steps

Ethereal hydrogen chloride is added dropwise to a solution of 1.0 g 1-[2-(2-naphthoyl)ethyl]imidazole in 100 ml anhydrous benzene until precipitation is complete. The product is filtered, washed with ether, air dried and recrystallized from methanol/acetone to yield 1-[2-(2-naphthoyl)ethyl]imidazole hydrochloride, m.p. 182.5°-186° C.

Provenance & Evidence