m-Chloroperbenzoic acid → HCID 178502524, compound

Participants

Reaction Steps

To a solution of 3.9 g (0.01 mole) of [[[2-(acetylamino)-4-[(2-methylpropyl)thio]phenyl]amino][(methoxycarbonyl)amino]methylene carbamic acid, methyl ester in 250 ml of chloroform there is added 2.0 g (0.01 mole of 85% m-chloroperoxybenzoic acid in 10 ml of chloroform with ice bath cooling. The reaction mixture is allowed to warm to room temperature and then stirred for 3 hours. The reaction mixture is washed with aqueous potassium carbonate and then with water until the pH is 7. The organic layer is dried (MgSO4), filtered, and evaporated in vacuo. The residue is crystallized from ethanol to yield 1.8 g, m.p. 178°-180° C. dec.

Provenance & Evidence