2-Bromopropionic acid → N-[3-[3-[1-(1-pyrrolidinyl)ethyl]phenoxy]propyl]bromopropionamide

HRID 847742Notes

Reaction equation

HRID 847742 reaction equation
[N:1]1([CH:6]([C:8]2[CH:9]=[C:10]([CH:16]=[CH:17][CH:18]=2)[O:11][CH2:12][CH2:13][CH2:14][NH2:15])[CH3:7])[CH2:5][CH2:4][CH2:3][CH2:2]1.[Br:19][CH:20]([CH3:24])[C:21](O)=[O:22]>>[N:1]1([CH:6]([C:8]2[CH:9]=[C:10]([CH:16]=[CH:17][CH:18]=2)[O:11][CH2:12][CH2:13][CH2:14][NH:15][C:21](=[O:22])[CH:20]([Br:19])[CH3:24])[CH3:7])[CH2:2][CH2:3][CH2:4][CH2:5]1

Participants

3

Reactant 2

HCID 117292-Bromopropionic acidHCID 130179203-[3-[1-(1-Pyrrolidinyl)ethyl]phenoxy]propylamine

Product 1

HCID 20567120N-[3-[3-[1-(1-pyrrolidinyl)ethyl]phenoxy]propyl]bromopropionamide

Procedure

3-[3-[1-(1-Pyrrolidinyl)ethyl]phenoxy]propylamine and bromopropionic acid were reacted in the same way as in Example 6 to afford N-[3-[3-[1-(1-pyrrolidinyl)ethyl]phenoxy]propyl]bromopropionamide.

Sources & evidence

ORD record
ord-b9f38bf4b0e946149678838947b0a221
Source dataset
uspto-grants-1981_10
Patent number
US04293557

Reaction notes

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