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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 847869Generated: October 30, 2026

(2-Isothiocyanatoethyl)dimethylamine → N-(2-Dimethylaminoethyl)-N'-[2-(2-pyrimidylmethylamino)ethyl]thiourea

https://huagongshe.com/reaction/847869

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(2-Isothiocyanatoethyl)dimethylamineHCID 3853726—
ReactantN-(2-pyrimidylmethyl)ethylenediamineHCID 20557649—
ProductN-(2-Dimethylaminoethyl)-N'-[2-(2-pyrimidylmethylamino)ethyl]thioureaHCID 20557883—

Reaction Steps

Treating N-(2-pyrimidylmethyl)ethylenediamine with 2-dimethylaminoethyl isothiocyanate, then concentrating and separating by column chromatography by the procedure of Example 40 (a)(ii) gives the title compound.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04293697
Source datasetuspto-grants-1981_10
ORD IDord-b28ad97141f14698876431080805b647
Source noteuspto-grants-1981_10