HuagongsheHuagongshe Chemistry Print Report · For research reference only
Benzoyl isothiocyanate → N-benzoyl-N'-[2-(2-thiazolylmethylthio)ethyl]thiourea
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Benzoyl isothiocyanate | HCID 68284 | — |
| Reactant | 2-[(Thiazol-2-yl)methylthio]ethylamine | HCID 12923403 | — |
| Product | N-benzoyl-N'-[2-(2-thiazolylmethylthio)ethyl]thiourea | HCID 20557654 | — |
Reaction Steps
By the procedure of Example 18, 2-[(2-aminoethyl)-thiomethyl]thiazole is reacted with benzoyl isothiocyanate to give N-benzoyl-N'-[2-(2-thiazolylmethylthio)ethyl]thiourea. Removing the benzoyl group by the procedure of Example 18 gives N-[2-(2-thiazolylmethylthio)ethyl]thiourea. Treating this compound with hydrobromic acid gives the hydrobromide salt.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04293697 |
| Source dataset | uspto-grants-1981_10 |
| ORD ID | ord-9a8cfdd6f8624a6c834c2300a859ab90 |
| Source note | uspto-grants-1981_10 |