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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 847896Generated: October 29, 2026

Methyl isothiocyanate → N-methyl-N'-[2-(3-isoxazolylmethoxy)ethyl]thiourea

https://huagongshe.com/reaction/847896

Reaction equation

Participants

RoleNameHCIDCharge
ReactantMethyl isothiocyanateHCID 11167—
Reactant3-(Chloromethyl)-1,2-oxazoleHCID 4913025—
Reactant3-(2-Chloroethoxymethyl)isoxazoleHCID 20557662—
ProductN-methyl-N'-[2-(3-isoxazolylmethoxy)ethyl]thioureaHCID 20557841—

Reaction Steps

By the procedure of Example 38, 3-chloromethylisoxazole is converted to 3-(2-chloroethoxymethyl)isoxazole which is then reacted with methyl isothiocyanate to give N-methyl-N'-[2-(3-isoxazolylmethoxy)ethyl]thiourea.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04293697
Source datasetuspto-grants-1981_10
ORD IDord-37fcbeefe5af41a48f2c362714873e36
Source noteuspto-grants-1981_10